Version: 8.0.0
Date: Tue Jan 28 2025
Gt(ROSA)26Sortm6(dre/PGR*)Dwi
MGI:6719400
Allele of Gt(ROSA)26Sor
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gt(ROSA)26Sortm6(dre/PGR*)Dwi

Species
Mus musculus
Symbol
Gt(ROSA)26Sortm6(dre/PGR*)Dwi
Category
allele
Allele of gene
Gt(ROSA)26Sor
Transgenic Constructs
Synonyms
  • RDrePr
Description
A splice acceptor site was inserted immediately before the Dre and the mutated human progesterone receptor (PGR) consisting of the Ru486 responsive mutant hormone-binding domain hPR891 was fused to the N-terminus of Dre sequence followed by a bovine growth hormone (BGH) polyadenylation signal and PGK-Puro selection cassette. The targeting vector was inserted into a Gt(ROSA)26Sor site by homologous recombination in ES cells.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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