Allele/Variant

Elavl2tm1.2Ysa

Species
Mus musculus
Symbol
Elavl2tm1.2Ysa
Category
allele
Allele of gene
Elavl2
Transgenic Constructs
None
Synonyms
  • Elavl2delta
  • Elavl2deltadeltaNeo
Description
By homologous recombination targeting in ES cells, the exon (ENSMUSE00001275521) including the start codon was flanked by loxP sequences and was followed by a Pgk-neo cassette flanked by Frt sequences. The Pgk-neo cassette was removed by crossing with Rosa-Flp mice. Mice were crossed to mice expressing cre in germline to delete the exon containing the start codon. Western blot analysis confirmed the absence of protein expression in newborn ovaries from homozygous mutant females. This is a null allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations