Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Runx1/Hspa1a-cre/ERT2)5-2Itoy
MGI:6726405Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Runx1/Hspa1a-cre/ERT2)5-2Itoy

Species
Mus musculus
Symbol
Tg(Runx1/Hspa1a-cre/ERT2)5-2Itoy
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • eR1-CreERT2(5-2)
Description
The transgenic construct contains mouse Runx1 enhancer element sequence (eR1) and the mouse Hspa1a (heat-shock protein 68) basal promoter sequence driving the expression of cre/ERT2. More than 10 founder lines were generated. The line TG(5-2) with higher copy number and TG(3-7) with lower copy number used for studies. Although the former had higher Cre recombinase activity than the latter, the results obtained using these lines were qualitatively indistinguishable.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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