Allele/Variant

Lmod1em1(IMPC)J

Species
Mus musculus
Symbol
Lmod1em1(IMPC)J
Category
allele
Allele of gene
Lmod1
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TCTTCGGTTGAGTTCTGTAG and TCCCAGAGCCAATTAGGCCT, which resulted in a 4824 bp deletion beginning at Chromosome 1 position 135,291,253 bp and ending after 135,296,076 bp (GRCm39/mm39). This mutation deletes ENSMUSE00000396118 and ENSMUSE00000361252 (exons 2 and 3) and 1340 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 87 and early truncation 51 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations