Allele/Variant

Creld2tm1.1Emass

Species
Mus musculus
Symbol
Creld2tm1.1Emass
Category
allele
Allele of gene
Creld2
Transgenic Constructs
None
Synonyms
  • Creld2eGFP
Description
The targeting vector is designed to replace the entire coding region of the gene with an enhanced green fluorescent protein (EGFP) sequence. An FRT-flanked neomycin resistance (neo) cassette with a polyadenylation signal (polyA) in reverse orientation to the gene were inserted into the 3' UTR. FLP-mediated recombination removed the FRT-flanked neo cassette. Immunoblot analysis confirmed the absence of protein expression in various tissues of homozygous mutant mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations