Allele/Variant

Mrps12em1.2Afi

Species
Mus musculus
Symbol
Mrps12em1.2Afi
Category
allele
Allele of gene
Mrps12
Transgenic Constructs
None
Synonyms
  • Mrps12ep
Description
CRISPR-targeting floxed the endogenous exon 2 and inserted an exon 2 with nucleotide substitutions encoding the amino acid substitution lysine to isoleucine at position 72 (K72I). This mutation produces a protein prone to translation error (ep). Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. Cre-mediated recombination removed the endogenous exon 2.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations