Mrps12^em2.2Afi

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Species

Mus musculus

Symbol

Mrps12^em2.2Afi

Category

allele

Allele of gene

Mrps12

Transgenic Constructs

None

Synonyms

• Mrps12^ha

Description

CRISPR-targeting floxed the endogenous exon 2 and inserted an exon 2 with a point mutations encoding the amino acid substitution lysine to threonine at position 71 (K71T). This mutation produces a protein with hyper-accurate translation (ha). Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. Cre-mediated recombination removed the endogenous exon 2.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations