Dpp4^em1(DPP4)Mbp

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Species

Mus musculus

Symbol

Dpp4^em1(DPP4)Mbp

Category

allele

Allele of gene

Dpp4

Transgenic Constructs

Synonyms

None

Description

CRISPR-targeting inserted exons 2-26 of human DPP4 in-frame into exon 2 of the mouse gene. The insert contains four silent mutations in the coding sequence to prevent CRISPR RNP re-cleavage (see HGVS nomenclature below); it uses the human 3' UTR to terminate transcription and to prevent potential downstream splicing or RNP re-cleavage.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations