Allele/Variant

Samd3tm1.1(HBEGF)Wfkr

Species
Mus musculus
Symbol
Samd3tm1.1(HBEGF)Wfkr
Category
allele
Allele of gene
Samd3
Transgenic Constructs
Synonyms
  • Samd3myrtdT-DTR2WK
  • Samd3TD
Description
The targeting construct introduced upstream of exon 2 a loxP site and downstream of exon 2 an inverted FRT-flanked tdTomato reporter gene and human diphtheria toxin receptor (HBEGF) with a single loxP site. Cre-mediated converted the reporter into the correct orientation.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
abnormal NK cell differentiationMGI
decreased CD8-positive, alpha-beta memory T cell numberMGI
decreased memory T cell numberMGI
decreased NK cell numberMGI
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Disease Associations

No data available