Allele/Variant

Tg(KRT18*R89C)50Rgo

Species
Mus musculus
Symbol
Tg(KRT18*R89C)50Rgo
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
This transgene consists of the human keratin 18 cDNA containing an arginine to cysteine substitution at amino acid 89 in exon 1. Three lines were generated; F22, F30, and F50. The transgene copy number for line F50 is 18. The relative protein ratio of endogenous mouse Krt18 to over-expressed human KRT18 is 1:1.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations