Version: 8.0.0
Date: Tue Jan 28 2025
Gata4em1Vigr
MGI:7280955
Allele of Gata4
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gata4em1Vigr

Species
Mus musculus
Symbol
Gata4em1Vigr
Category
allele
Allele of gene
Gata4
Transgenic Constructs
None
Synonyms
  • GATA4 S261A
Description
Using an sgRNA and an ssODN template (gctcccaagggactatcctggcctagccctgctaaacacaaaacacttcctttctatgttgtagGcGgcttcccgccgggtaggcctctcctgtgccaactgccagactaccaccaccacg) with CRISPR/Cas9 technology, serine codon 261 (TCC) was changed to alanine (GCG) (p.S261A). This mutation blocks the phosphorylation of the residue.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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