Allele/Variant

Hsf2bpem1Amp

Species
Mus musculus
Symbol
Hsf2bpem1Amp
Category
allele
Allele of gene
Hsf2bp
Transgenic Constructs
None
Synonyms
  • Hsf2bp-
Description
CRISPR/Cas9 technology, using an sgRNA (targeting TCACAAAACTCTCCATCGTC and ATTGGATGGGGATGTCAAGG), generated a 28 bp deletion (GACATCCCCATCCAATGACTTCACAAAA, GRCm39:chr17:32230208-32230235) in exon 5, leading to a frameshift and premature stop codon (p.Ser167Argfs*19). Western blot analysis confirmed absence of protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations