Taok1^em1(IMPC)Tcp

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Species

Mus musculus

Symbol

Taok1^em1(IMPC)Tcp

Category

allele

Allele of gene

Taok1

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GAAAAGCAAATACCGCCGGG targeting the 5' side and AAACATTAAACTAGGCGGTC targeting the 3' side of a critical region (ENSMUSE00000520605) along with a single-strand oligonucleotide encoding a Bxb1 attB site. This resulted in a 1292-bp deletion of Chr11 from 77,465,754 to 77,467,045 (GRCm39) with an insertion of a Bxb1 attB sequence (GGCTTGTCGACGACGGCGGTCTCCGTCGTCAGGATCATACACCGG).

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations