Irgq^em1(IMPC)J

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Species

Mus musculus

Symbol

Irgq^em1(IMPC)J

Category

allele

Allele of gene

Irgq

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACAGTGAATCAGTTAGGAGA and CCATGTGCTTGTCTACGGAG, which resulted in a 7630 bp deletion beginning at Chromosome 7 position 24,531,163 bp and ending after 24,538,792 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000404079 and ENSMUSE00000317876 (exons 2 and 3) and 1763 bp of intronic sequence including the splice acceptor and donor the start site and 3’ UTR and is predicted to result in a null allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations