Timm17b^em1(IMPC)J

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Species

Mus musculus

Symbol

Timm17b^em1(IMPC)J

Category

allele

Allele of gene

Timm17b

Transgenic Constructs

None

Synonyms

None

Description

This was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCAGCAGCCAAAGAACCAGG and CCCCACAGTCTAATATGAAA, which resulted in a 414 bp deletion beginning at Chromosome X position 7,903,461 bp and ending after 7,903,874 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000206943 (exon 3) and 350 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 42 and early truncation 34 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations