The line was obtained by microinjection of a circular human BAC transgene (RP11-64B17) previously modified by recombineering at the ATG of the CD19 gene of a rabbit-beta-globin intron-cre/ERT2 cassette followed by a flipped PGK-Tn5-Kana/NeoR cassette. The subline 61.2 was analyzed and cryopreserved.