Allele/Variant

Ap5s1em1(IMPC)J

Species
Mus musculus
Symbol
Ap5s1em1(IMPC)J
Category
allele
Allele of gene
Ap5s1
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCAGGCACTAGATTATTCAG and AGCAGACTCCCACTCACAAG, which resulted in a 2400 bp deletion beginning at Chromosome 2 position 131,211,143 bp and ending after 131,213,542 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000558540, ENSMUSE00001373302, ENSMUSE00000558538 (exons 2, 3, and 4) and 1210 bp of flanking intronic sequence including the start site, splice acceptor and donor and is predicted to result in a null allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations