Allele/Variant

Mpndem1(IMPC)J

Species
Mus musculus
Symbol
Mpndem1(IMPC)J
Category
allele
Allele of gene
Mpnd
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGCCTGGACCAACCGCCAGA and ATCAGGATTCAGGATTCCCC, which resulted in a 389 bp deletion beginning at Chromosome 17 position 56,010,881 bp and ending after 56,011,269 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001271227 (exon 4) and 265 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 167 and early truncation 33 amino acids later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations