Hs1bp3^em1(IMPC)J

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Species

Mus musculus

Symbol

Hs1bp3^em1(IMPC)J

Category

allele

Allele of gene

Hs1bp3

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCTTCGTCTGACGTTCCCCA and AGACCTTGAACAAATGACAT, which resulted in a 463 bp deletion beginning at Chromosome 12 position 8,373,662 bp and ending after 8,374,124 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000106987 (exon 4) and 231 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 135 and early truncation 12 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations