Allele/Variant

Ubr7em1(IMPC)Tcp

Species
Mus musculus
Symbol
Ubr7em1(IMPC)Tcp
Category
allele
Allele of gene
Ubr7
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CCTTCCCTCTTCCGTTATGC targeting the 5' side and GGACTGGTTGGGAGCCTACC targeting the 3' side of a critical region (ENSMUSE00000259884, ENSMUSE00000259878, ENSMUSE00000259867, ENSMUSE00000343370 & ENSMUSE00000115512) along with a single-strand oligonucleotide encoding a Bxb1 attB site. This resulted in a 5,617-bp deletion of Chr12 from 102,727,155 to 102,732,771 (GRCm39) with insertion of the attB sequence (GGCTTGTCGACGACGGCGGTCTCCGTCGTCAGGATCATACACCGG).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations