Allele/Variant

Trim10em1(IMPC)J

Species
Mus musculus
Symbol
Trim10em1(IMPC)J
Category
allele
Allele of gene
Trim10
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTTTACTGCCTAACCTTGGG and CTTTTTCTAACAAGGCCTTG, which resulted in a 1354 bp deletion beginning at Chromosome 17 position 36,872,172 bp and ending after 36,873,525 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000357218 and ENSMUSE00000657361 (exons 3 and 4) and 1100 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 175 and early truncation 1 amino acid later.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations