Allele/Variant

Adissptm1c(EUCOMM)Hmgu

Species
Mus musculus
Symbol
Adissptm1c(EUCOMM)Hmgu
Category
allele
Allele of gene
Adissp
Transgenic Constructs
None
Synonyms
  • Adissp flox
Description
The L1L2_gt1 cassette was inserted at position 130993292 of Chromosome 2 upstream of the critical exon 3 (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon 3 at position 130994101. The critical exon 3 is thus flanked by loxP sites. Flp-mediated recombination removed the lacZ/neomycin sequence and generated a "conditional ready" (floxed) allele. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations