Mybph^em1(IMPC)J

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Species

Mus musculus

Symbol

Mybph^em1(IMPC)J

Category

allele

Allele of gene

Mybph

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCTGTAGGAACGTCGTAGGT and GGTGGGGAGAGAAGTAGTCG, which resulted in a 1002 bp deletion beginning at Chromosome 1 position 134,124,648 bp and ending after 134,125,649 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000252306, ENSMUSE00000252298 and ENSMUSE00000252292 (exons 4, 5 and 6) and 577 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 175 and early truncation 40 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations