Version: 8.0.0
Date: Tue Jan 28 2025
Sim1tm1.1(cre)Lowl
MGI:7444470
Allele of Sim1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Sim1tm1.1(cre)Lowl

Species
Mus musculus
Symbol
Sim1tm1.1(cre)Lowl
Category
allele
Allele of gene
Sim1
Transgenic Constructs
Synonyms
  • Sim1-IRES-Cre
Description
A selection cassette containing an internal ribosomal entry sequence (IRES) linked to Cre-recombinase and an Frt-flanked neomycin resistance gene was targeted 3 bp after the stop codon of the Sim1 gene, so that Cre-recombinase expression was driven by the endogenous gene. Flpe recombinase transgene mice were then used to remove the neomycin selection cassette.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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