Kcng1^em1(IMPC)Tcp

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Species

Mus musculus

Symbol

Kcng1^em1(IMPC)Tcp

Category

allele

Allele of gene

Kcng1

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of AGGTGGCGCTGACTTAACAT targeting the 5' side and TGGTTGCATGAAGCCGCAGC targeting the 3' side flanking the CDS (ENSMUSE00000679346 & ENSMUSE00000639006). This resulted in a 7,713-bp deletion of Chr2 from 168,104,267 to 168,111,979 (GRCm39) introducing a frameshift and premature stop codon.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations