Allele/Variant

Trappc8em1(IMPC)Tcp

Species
Mus musculus
Symbol
Trappc8em1(IMPC)Tcp
Category
allele
Allele of gene
Trappc8
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CCGGCTCAAAATGTCTAGAT targeting the 5' side and CAGGTGTGAACTAGTACCAT targeting the 3' side of a critical region from exon 3 to exon 8 (ENSMUSE00000379803, ENSMUSE00000277191, ENSMUSE00000277177, ENSMUSE00000344646, ENSMUSE00000409531, and ENSMUSE00000277110). This resulted in a 10,577-bp deletion of Chr18 from 20997797 to 21008373 (GRCm39) introducing a frameshift and premature stop codon.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations