Allele/Variant

Scaf8em1(IMPC)J

Species
Mus musculus
Symbol
Scaf8em1(IMPC)J
Category
allele
Allele of gene
Scaf8
Transgenic Constructs
None
Synonyms
None
Description
This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GAGAGACTAAAATAGTTCAG and GTTCACACGCTATAGGGCAG, which resulted in a 457 bp deletion beginning at Chromosome 17 position 3,162,731 bp and ending after 3,163,187 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000345755 (exon 5) and 303 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 107 and early truncation 3 amino acids later. There is a 4 bp insertion (CTTC) at the deletion site.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations