Version: 8.0.0
Date: Tue Jan 28 2025
Runx3tm1.1Itok
MGI:7482709
Allele of Runx3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Runx3tm1.1Itok

Species
Mus musculus
Symbol
Runx3tm1.1Itok
Category
allele
Allele of gene
Runx3
Transgenic Constructs
None
Synonyms
  • Runx3(P1)delta
Description
A loxP site was inserted in exon one 5' of the N-terminal region and a loxP and FRT flanked neo cassette was inserted 3' of exon 1. Cre mediated recombination removed the neo cassette and the N-terminal region of exon 1. Western blot analysis confirmed the absence of expression of the RUNX3(P1) protein that has a distinct set of 19 N-terminal amino acids compared to the RUNX3(P2) protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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