2210408F21Rik^em1Liuq

---

Species

Mus musculus

Symbol

2210408F21Rik^em1Liuq

Category

allele

Allele of gene

2210408F21Rik

Transgenic Constructs

None

Synonyms

• Pair^-

Description

Two point mutations, chr6:31197455G>A and chr6:31197457A>T (GRCm39), were created using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutations in intron 1 eliminate the exon 1 splice donor site, changing it from from G-GTA to G-ATT, which virtually eliminates transcript expression from this allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations