Iars1^em2Nsas

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Species

Mus musculus

Symbol

Iars1^em2Nsas

Category

allele

Allele of gene

Iars1

Transgenic Constructs

None

Synonyms

• Iars^{em2(V79L)Nsas}
• IARS1^V79L

Description

Valine codon 79 (GTT) in exon 3 was changed to leucine (CTT) (NM_172015.3:c.235G>C, p.V79L) using a crRNA (targeting TGTCAACGTGAAACCCGCTC) and an ssODN template with CRISPR/Cas9 technology. The mutation is associated with weak calf syndrome in cattle.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations