Ddx17^em1(IMPC)J

---

Species

Mus musculus

Symbol

Ddx17^em1(IMPC)J

Category

allele

Allele of gene

Ddx17

Transgenic Constructs

None

Synonyms

None

Description

This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTATTCTGAAAAATTACAAG and CTATCTTTACTAGTAAACTA, which resulted in an 820 bp deletion beginning at Chromosome 15 position 79,540,391 bp and ending after 79,541,210 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000260669 and ENSMUSE00000557611 (exons 4 and 5) and 620 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 100 and early truncation 18 amino acids later.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations