Allele/Variant

Leprdb-Nokl

Species
Mus musculus
Symbol
Leprdb-Nokl
Category
allele
Allele of gene
Lepr
Transgenic Constructs
None
Synonyms
  • LeprL536Hfs*6-1NKB
  • LeprL536Hfs*6
Description
This spontaneous mutation involves the deletion of a single nucleotide in exon 11 (GRCm39:chr4:101628503delT) in the cytokine receptor homology 2 (CRH2) leptin-binding domain of the encoded peptide, which causes a frameshift and premature stop codon (p.L536Hfs*6).
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations