Allele/Variant

Thsd4tm1.2Lysa

Species
Mus musculus
Symbol
Thsd4tm1.2Lysa
Category
allele
Allele of gene
Thsd4
Transgenic Constructs
None
Synonyms
None
Description
Exon 2 of the beta form, which is exon 8 of the alpha form, was flanked by loxP sites and an FRT-flanked neomycin cassette was inserted. This codes for part of the “spacer” region, a motif shared by other members of this family. Deletion leads to a frameshift variant with predicted loss of any remaining protein. Flp-mediated recombination removed the neomycin cassette. Exon2/8 was removed via cre-mediated recombination.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations