Spin4^em2Jbn

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Species

Mus musculus

Symbol

Spin4^em2Jbn

Category

allele

Allele of gene

Spin4

Transgenic Constructs

None

Synonyms

• short-deletion

Description

CRISPR/Cas9 genome editing technology was used to generate a truncating deletion of sequences downstream of the second Tudor domain of the encoded protein. This line has only Tudor domain 3 removed. Histone array analysis demonstrated that the truncated protein has severely diminished histone-binding capacity.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations