Version: 8.0.0
Date: Tue Jan 28 2025
Mtarc1tm1.1Vlcg
MGI:7623614
Allele of Mtarc1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Mtarc1tm1.1Vlcg

Species
Mus musculus
Symbol
Mtarc1tm1.1Vlcg
Category
allele
Allele of gene
Mtarc1
Transgenic Constructs
None
Synonyms
  • Marc1-
Description
Exons 2 and 3 were replaced with a lacZ reporter, loxP site, self-deleting protamine promoter, cre recombinase, neomycin selection cassette and second loxP site using Regeneron’s VelociGene technology. The neomycin selection marker located between two loxP sites was deleted with cre recombinase under self-deleting protamine promoter, leaving beta-galactosidase gene (LacZ) and one loxP site in the flanking intron. Western blot analysis confirmed the absence of protein in liver lysates.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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