Ctps2^{tm1d(EUCOMM)Hmgu}

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Species

Mus musculus

Symbol

Ctps2^{tm1d(EUCOMM)Hmgu}

Category

allele

Allele of gene

Ctps2

Transgenic Constructs

None

Synonyms

• Ctps2^ko

Description

The L1L2_GT0_LF2A_LacZ_BetactP_neo cassette was inserted at position 161708956 of Chromosome X upstream of the critical exon 8 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 8 at position 161710712. The critical exon 8 is thus flanked by loxP sites. The lacZ and neomycin resistance gene were removed via flp-mediated recombination. Exon 8 was deleted via cre-mediated recombination, generating a knock-out allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations