Lrrk1^em1SageLrrk2^em1Sage

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Species

Rattus norvegicus

Symbol

Lrrk1^em1SageLrrk2^em1Sage

Category

allele

Allele of gene

Lrrk1

Transgenic Constructs

None

Synonyms

• Lrrk1em1SageLrrk2em1Sage

Description

leucine-rich repeat kinase 1, leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs; This allele was made by ZFN mutagenesis. The resulting mutations are a 19-bp frameshift deletion (TGCCTCGCAGCGGCTGCTG) in exon 4 of Lrrk1 and a 10-bp frameshift deletion (CCCAGAGAGC) in exon 30 of Lrrk2.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations