Disease

desmoplastic infantile ganglioglioma / desmoplastic infantile astrocytoma

Definition
A ganglioglioma occurring predominantly in the cerebral hemispheres of infants, that are driven by MAPK pathway activation and composed of a mixed astrocytic and neuronal component (DIG) or an astrocytic component only (DIA) embedded in an extensive desmoplastic stroma, often containing foci of undifferentiated embryonal-like tumour cells.
Synonyms
  • Desmoplastic Infantile Astrocytoma
  • desmoplastic infantile ganglioglioma
Cross References
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