Gene

al

Species
Drosophila melanogaster
Symbol
al
Name
aristaless
Synonyms
  • A1
  • Al
Biotype
protein coding gene
Automated Description
Contributes to sequence-specific DNA binding activity. Involved in chaeta development; imaginal disc-derived appendage morphogenesis; and negative regulation of DNA-templated transcription. Part of protein-containing complex. Is expressed in several structures, including gut section; imaginal disc; organism subdivision; sense organ; and sensory nervous system primordium. Human ortholog(s) of this gene implicated in X-linked lissencephaly 2; X-linked recessive disease (multiple); corpus callosum agenesis-abnormal genitalia syndrome; and syndromic X-linked intellectual disability Hedera type. Orthologous to human ARX (aristaless related homeobox).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24329
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
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Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions