Gene

BicC

Species
Drosophila melanogaster
Symbol
BicC
Name
Bicaudal C
Synonyms
  • BG:DS00913.2
  • Bic-C
Biotype
protein coding gene
Automated Description
Enables mRNA binding activity. Involved in actin cytoskeleton organization and microtubule cytoskeleton organization. Predicted to be active in cytoplasm. Is expressed in germarium region 2a; germarium region 2b; germarium region 3; nurse cell; and oocyte. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Orthologous to human BICC1 (BicC family RNA binding protein 1).
FB Description
Bicaudal C (BicC) encodes an RNA binding protein that interacts with the deadenylase encoded by twin and negatively regulates target mRNAs. It is required for oogenesis and is a maternally-expressed gene involved in embryonic patterning.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10627
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
16.043M16.044M16.045M16.046M16.047M16.048M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions