Predicted to enable clathrin light chain binding activity. Involved in several processes, including compound eye retinal cell programmed cell death; germ cell development; and open tracheal system development. Located in several cellular components, including clathrin-coated pit; cytoplasmic vesicle; and trans-Golgi network. Is expressed in several structures, including adult head; epidermis; gland; gut section; and imaginal disc. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 56. Orthologous to human CLTC (clathrin heavy chain) and CLTCL1 (clathrin heavy chain like 1).
FB Description
Clathrin heavy chain (Chc) encodes a protein that forms part of the clathrin complex, which is the major component of coated vesicles.