Gene

Chc

Species
Drosophila melanogaster
Symbol
Chc
Name
Clathrin heavy chain
Synonyms
  • CG9012
  • CHC
Biotype
protein coding gene
Automated Description
Predicted to enable clathrin light chain binding activity. Involved in several processes, including compound eye retinal cell programmed cell death; germ cell development; and open tracheal system development. Located in several cellular components, including clathrin-coated pit; cytoplasmic vesicle; and trans-Golgi network. Is expressed in several structures, including adult head; epidermis; gland; gut section; and imaginal disc. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 56. Orthologous to human CLTC (clathrin heavy chain) and CLTCL1 (clathrin heavy chain like 1).
FB Description
Clathrin heavy chain (Chc) encodes a protein that forms part of the clathrin complex, which is the major component of coated vesicles.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10292
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
15.828M15.829M15.830M15.831M15.832M15.833M15.834M15.835M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions