Gene

fw

Species
Drosophila melanogaster
Symbol
fw
Name
furrowed
Synonyms
  • CG1500
  • CT3745
Biotype
protein coding gene
Automated Description
Predicted to enable carbohydrate binding activity. Involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; imaginal disc-derived wing hair organization; and protein stabilization. Located in apical junction complex. Is expressed in adult head; embryonic/larval proventriculus; eye; and larval brain. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to several human genes including SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1).
FB Description
furrowed (fw) encodes a selectin that mediates the interaction of planar cell polarity proteins by stabilizing the product of fz.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19325
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
11.993M11.994M11.995M11.996M11.997M11.998M11.999M12.000M12.001M12.002M12.003M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions