Predicted to enable carbohydrate binding activity. Involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; imaginal disc-derived wing hair organization; and protein stabilization. Located in apical junction complex. Is expressed in adult head; embryonic/larval proventriculus; eye; and larval brain. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to several human genes including SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1).
FB Description
furrowed (fw) encodes a selectin that mediates the interaction of planar cell polarity proteins by stabilizing the product of fz.