Gene

LanA

Species
Drosophila melanogaster
Symbol
LanA
Name
Laminin A
Synonyms
  • alpha[[3,5]]
  • alpha3,5 laminin
Biotype
protein coding gene
Automated Description
Predicted to be an extracellular matrix structural constituent. Involved in several processes, including dorsal trunk growth, open tracheal system; melanotic encapsulation of foreign target; and negative regulation of synaptic assembly at neuromuscular junction. Located in basement membrane and presynaptic periactive zone. Is expressed in several structures, including embryonic/larval midgut primordium; germ layer; glial cell; head epidermis primordium; and hemocyte. Human ortholog(s) of this gene implicated in bent bone dysplasia syndrome 2; familial nephrotic syndrome; junctional epidermolysis bullosa; and lung small cell carcinoma. Orthologous to several human genes including LAMA5 (laminin subunit alpha 5).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10574
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
6.204M6.206M6.208M6.210M6.212M6.214M6.216M6.218M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions