Involved in several processes, including RNA splicing; oocyte microtubule cytoskeleton polarization; and regulation of pole plasm oskar mRNA localization. Located in nucleus and pole plasm. Part of exon-exon junction complex. Is expressed in several structures, including antennal anlage; embryonic/larval midgut primordium; female germline cell; ganglia; and head epidermis primordium. Orthologous to human MAGOHB (mago homolog B, exon junction complex subunit) and MAGOH (mago homolog, exon junction complex subunit).
FB Description
mago nashi (mago) encodes a protein that is part of the exon junction complex, which is required for post-transcriptional processes such as pre-mRNA splicing, RNA localization and nonsense-mediated decay. It is involved in germline development, germplasm assembly and photoreceptor differentiation.