Enables DNA-directed DNA polymerase activity. Involved in DNA synthesis involved in double-strand break repair via homologous recombination. Part of zeta DNA polymerase complex. Is expressed in spermatozoon and wing disc. Orthologous to human REV3L (REV3 like, DNA directed polymerase zeta catalytic subunit).
FB Description
DNA polymerase zeta subunit 1 (PolZ1) encodes a DNA polymerase zeta catalytic subunit. It acts as a translesion polymerase during the bypass of DNA damage and has roles in DNA double-strand break and interstrand crosslink repair.