Gene

PolZ1

Species
Drosophila melanogaster
Symbol
PolZ1
Name
DNA polymerase zeta subunit 1
Synonyms
  • 154926_at
  • AAF59191
Biotype
protein coding gene
Automated Description
Enables DNA-directed DNA polymerase activity. Involved in DNA synthesis involved in double-strand break repair via homologous recombination. Part of zeta DNA polymerase complex. Is expressed in spermatozoon and wing disc. Orthologous to human REV3L (REV3 like, DNA directed polymerase zeta catalytic subunit).
FB Description
DNA polymerase zeta subunit 1 (PolZ1) encodes a DNA polymerase zeta catalytic subunit. It acts as a translesion polymerase during the bypass of DNA damage and has roles in DNA double-strand break and interstrand crosslink repair.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45812
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
7.794M7.795M7.796M7.797M7.798M7.799M7.800M7.801M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions