Gene

yrt

Species
Drosophila melanogaster
Symbol
yrt
Name
yurt
Synonyms
  • CG9764
  • dlhB
Biotype
protein coding gene
Automated Description
Predicted to enable cytoskeletal protein binding activity. Involved in embryonic development via the syncytial blastoderm; establishment of epithelial cell apical/basal polarity; and eye photoreceptor cell development. Located in apical junction complex; basolateral plasma membrane; and nuclear envelope. Is expressed in larval tracheal system. Orthologous to human EPB41L4B (erythrocyte membrane protein band 4.1 like 4B) and EPB41L5 (erythrocyte membrane protein band 4.1 like 5).
FB Description
yurt (yrt) encodes a membrane-associated protein. It contributes to apical-basal polarity and permeability of septate junctions. In differentiating epithelial cells, it counteracts apical polarity proteins to sustain lateral membrane stability and apical-basal polarity. In fully differentiated cells, the product of yrt acts as a negative regulatory component of the crb complex and limits apical membrane growth.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23280
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
13.429M13.430M13.431M13.432M13.433M13.434M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions