Gene

mei-41

Species
Drosophila melanogaster
Symbol
mei-41
Name
meiotic 41
Synonyms
  • 4252
  • Ataxia Telangiectasia and Rad3 related
Biotype
protein coding gene
Automated Description
Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including DNA metabolic process; female meiosis chromosome segregation; and regulation of cell cycle process. Predicted to be active in chromosome and nucleus. Is expressed in ovary. Human ortholog(s) of this gene implicated in Seckel syndrome 1; adenoid cystic carcinoma; colon cancer; lung cancer; and pancreatic cancer. Orthologous to human ATR (ATR serine/threonine kinase).
FB Description
meiotic 41 (mei-41) encodes a protein that, together with mus304, promotes DNA damage-dependent responses, including repair and cell cycle checkpoint signalling.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11139
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

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    Disease Associations

    Cases where the expected disease association was NOT found
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      Alleles and Variants

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        Transgenic Alleles

        Species
        (carrying the transgene)
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            R6
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            16.392M16.393M16.394M16.395M16.396M16.397M16.398M16.399M

            Sequence Details

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            Expression

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            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            mei-41 molecule type
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              Genetic Interactions

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              mei-41 genetic perturbation
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