Gene

rho

Species
Drosophila melanogaster
Symbol
rho
Name
rhomboid
Synonyms
  • CG1004
  • Dmel\rho
Biotype
protein coding gene
Automated Description
Enables serine-type endopeptidase activity. Involved in several processes, including neuron differentiation; open tracheal system development; and wing disc development. Located in Golgi membrane; apical part of cell; and late endosome membrane. Is expressed in several structures, including epithelium; eye photoreceptor cell; presumptive wing vein; sense organ; and wing vein. Used to study alcohol use disorder. Orthologous to several human genes including RHBDL1 (rhomboid like 1) and RHBDL3 (rhomboid like 3).
FB Description
rhomboid (rho) encodes an intra-membrane serine protease that processes the membrane precursors of Egfr ligands. Its roles include growth regulation, cell survival and developmental patterning.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR45840
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
1.4640M1.4645M1.4650M1.4655M1.4660M1.4665M1.4670M1.4675M1.4680M1.4685M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions