Enables serine-type endopeptidase activity. Involved in several processes, including neuron differentiation; open tracheal system development; and wing disc development. Located in Golgi membrane; apical part of cell; and late endosome membrane. Is expressed in several structures, including epithelium; eye photoreceptor cell; presumptive wing vein; sense organ; and wing vein. Used to study alcohol use disorder. Orthologous to several human genes including RHBDL1 (rhomboid like 1) and RHBDL3 (rhomboid like 3).
FB Description
rhomboid (rho) encodes an intra-membrane serine protease that processes the membrane precursors of Egfr ligands. Its roles include growth regulation, cell survival and developmental patterning.