Gene

Wnt5

Species
Drosophila melanogaster
Symbol
Wnt5
Name
Wnt oncogene analog 5
Synonyms
  • anon-WO03040301.228
  • CG6407
Biotype
protein coding gene
Automated Description
Enables receptor ligand activity. Involved in several processes, including determination of muscle attachment site; neuron projection morphogenesis; and positive regulation of cell projection organization. Located in dendrite and extracellular region. Is expressed in several structures, including A1-7 lateral transverse muscle cell; head segment; neuromere; neuron projection bundle; and ventral thoracic disc primordium. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to human WNT5A (Wnt family member 5A) and WNT5B (Wnt family member 5B).
FB Description
Wnt oncogene analog 5 (Wnt5) encodes a member of the Wnt gene family and acts as a signalling ligand for the Ryk family of receptor tyrosine kinase-related Wnt receptors. Among other processes, the product of Wnt5 contributes to repulsive embryonic axon pathfinding, mushroom body growth and antennal lobe patterning.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12027
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
18.5015M18.5020M18.5025M18.5030M18.5035M18.5040M18.5045M18.5050M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions