Enables phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including defense response to bacterium; imaginal disc-derived male genitalia morphogenesis; and microvillus organization. Located in brush border and cell cortex. Is expressed in several structures, including adult head; epithelial cell; epithelium; gut section; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in congenital central hypoventilation syndrome. Orthologous to human MYO1C (myosin IC) and MYO1H (myosin IH).